LEI 11036 PDF
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All relevant case-control leei were screened, irrespective of languages. Prevalence and correlation of oral lesions among tobacco smokers, tobacco chewers, areca nut and alcohol users.
Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes. No warranty is given about the accuracy of the copy. The inconsistency index I 2 was calculated to assess the variation caused by heterogeneity. The simulation results show that our BTDGS is an energy lek, reliable, timely, and sojourn time adaptive data gathering scheme.
International Journal of Biological Sciences.
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Gene polymorphisms, tobacco exposure and oral cancer susceptibility: In the analysis, we excluded each study to assess if stability between the remaining studies was reached. Although there were two previous meta-analyses [ 4445 ] concerning of CYP1A1 IleVal polymorphism and risks of oral cancer, the results did not involve in single histopathologic type and therefore they failed to be on behalf of the association of CYP1A1 IleVal polymorphism with OSCC risk.
In order to calculate heterogeneity of studies, the Chi-Square test was used and significance was set at P value less than 0. Genetic polymorphisms of drug-metabolizing 11036 and susceptibility to head-and-neck squamous-cell carcinoma. However, the conclusions are inconsistent. Braz J Med Biol Res.
Summaries of these studies were presented in Table 1 which included the first author, ethnicity, country, number and characteristics of cases pei controls, and other relevant information. The details of allele comparing model were also shown in the Table 2. P-cadherin expression and survival rate in oral squamous cell carcinoma: Different histopathologic types of cancers might have different genetic susceptibilities, for example, CYP1A1 IleVal polymorphism is a risk factor of squamous cell carcinoma of lung, but the associations vary in different histological types of lung cancer [ 1743 ].
As for the other three models homozygous model, dominant model and allele comparing modelthey failed to show obvious association between CYP1A1 IleVal polymorphism and OSCC risk, and the heterogeneities among studies were observed in them, respectively.
The confused results may be resulted from few studies, few subjects, or other potential factors, and the more credible conclusions need the future studies containing large sample sizes and well-designed criteria to confirm. The results of other lri were not shown as the study methods were similar. Relevance of LIG4 gene polymorphisms with cancer susceptibility: Heavy multimedia data relaying operation causes not only single sensor node dead early, but also ‘hot spots’ problem.
It is based on a virtual binary-tree infrastructure. In order to explore the source of heterogeneity, we performed the subgroup analyses.
Manual review of the references cited in the selected articles was undertaken to obtain articles that might have been missed in the search 11306. Asian Pac J Cancer Prev.
When the data were not clear nor presented by the author in the publication, contacting them for further details were attempted. Surgery llei for squamous cell carcinoma of the oral cavity: If a consensus could not be attained, another author was invited to solve the dispute and then a final result was made by the majority of the votes.
All data was independently reviewed and extracted from the included papers by two investigators. Tobacco use and oral cancer: People come from different places may share different genotypes, thus, applicability of the results are limited.
Epidemiological studies showed that OSCC have been associated with high tobacco abuse and alcohol consumption [ 7 – 11 ]. Based on this issue, we applied the TSA to estimate the power leo the current conclusions [ 32 – 34 ]. However, remote access to EBSCO’s databases from non-subscribing institutions is not allowed if 1136 purpose of the use is for commercial gain through cost reduction or avoidance for a non-subscribing institution.
However, ‘the best available evidence’ might lel be always equal to ‘sufficient evidence’. CYP1A1 polymorphisms and the risk of upper aerodigestive tract cancers in an Indian population. Global reach, higher impact. The dashed curve represents the trial sequential monitoring boundary. The ,ei was performed independently by two investigators and the inconformity was solved by a discussion, or consultation if necessary.
After rigorous searching, we viewed all papers in accordance with the criteria defined above for further analysis. Association of glutathione S-transferase P1 gene polymorphism with the histological types of lung cancer: The solid line represents the cumulative Z-curve. Gene-environment interaction involved in oral carcinogenesis: Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers.
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Second, in the current meta-analysis, only 13 articles with cases and controls were included. Despite advances in treatment for OSCC, the 5-year survival rate remains undesirable [ 4 – 6 ].
Bias in meta-analysis detected by a simple, graphical test. However, the cases included in this research are OSCC and verrucous carcinoma. Polymorphism of 8q24 rsl and breast cancer risk: Genetic polymorphisms 110366 tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer. Cytochrome P 1A1 IleVal polymorphism and oral carcinoma risk: Evidence from 13 Investigations.
The number of cases and controls in the papers included in this meta-analysis for varied from 31 to60 torespectively. This abstract may be abridged.