Histoid leprosy is a skin condition, a rare form of multibacillary leprosy See also[edit]. Leprosy · Skin lesion. References[edit]. ^ James, William D.; Berger. Histoid leprosy, an uncommon variant of lepromatous leprosy, develops usually as relapse in lepromatous patients who are on dapsone. Summary Histoid leprosy is a rare multibacillary form that presents with disseminated papule-nodular cutaneous lesions. To study the inflammatory infiltrate.

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There was no impairment of pain, touch, or temperature sensation. Open histoix a separate window. Multiple well-demarcated, skin colored, grouped shiny nodules on a normal appearing skin over the back.

A retrospective study of 40 cases from India. Footnotes Source of support: Leprosy relapse presenting in histoid form after MDT. Histoid leprosy cases represent probable resistant bacilli and a highly active lepromatous process. How to cite histodi URL: Arch Argent Dermatol ; Please review jistoid privacy policy.

The nodules varied in size from 0. He did not take any form of treatment for his skin lesions. Abstract Histoid leprosy, an uncommon variant of lepromatous leprosy, develops usually as relapse in lepromatous patients who are on dapsone monotherapy, but uncommonly arises de novo. Histoid leprosy with no previous history of taking anti-leprosy treatment should be diagnosed as De novo case and MBMDT should be initiated with regular follow up.


Histoid lesions have also been found along the course of the peripheral nerve trunks and cutaneous nerves. Corynebacterium diphtheriae Diphtheria Corynebacterium minutissimum Erythrasma Corynebacterium jeikeium Group JK corynebacterium sepsis.

Lesions vary in size and consistency. The impact of the entity on the postglobal leprosy elimination era.

Histoid leprosy

The aetiopathogenesis of this entity leprksy not clear but leposy increased cell-mediated CM and humoral immunity against M. These cases may act as reservoirs of the disease and lead to further spread of leprosy. Each of them can be differentiated from the histoid leprosy on the basis of its characteristic histopathology, the absence of lepra bacilli on slit skin smear and nerve thickening. On correlating the clinical and histopathological findings we came to a diagnosis of Histoid leprosy.

The nodules were distributed predominantly over the trunk and thighs. Histoid leprosy HLinitially described by Wade, is considered by some as a variant of lepromatous leprosy LL ,and by others as distinct entity. Support Center Support Center.

The lesions were present for the last 1 leproosy. There was no thickening of peripheral nerves. Sitemap What’s New Feedback Disclaimer. Histoid leprosy is a variant of Lepromatous leprosy believed to occur due to a mutant strain of leprosy bacillus called as Histoid Bacillus.

This article has been cited by other articles in PMC. It exhibits a fibromatoid tendency in the chronic form.


Histoid leprosy – Wikipedia

Sengal VN, Srivastava G. These bacilli appear longer with tapering ends whenth compared to the ordinary lepra bacilli. Our patient was elderly, lepeosy This is an open-access article distributed under the terms of the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Related articles Multibacillary multidrug therapy Elimination. Indian J Med Microbiol ; Author information Article notes Copyright and License information Disclaimer. National Center for Biotechnology InformationU. The nodules were distributed on his low back, buttocks, arms, and abdomen.

It involves skin, peripheral nerves, and nasal mucosa but is capable of affecting any tissue. However, it has also been reported in patients who relapsed even on supervised monthly dose of multidrug therapy and in patients without any treatment [ 3 ]. Sehgal VN, Srivasta G.

Dermis showed diffuse collection of foamy macrophages and spindle shaped cells histiocytes Click here to view.

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