Dexmethylphenidate has a high potential for abuse. Administration of stimulants for a prolonged period of time may lead to physical and psychological drug. Focalin XR should be given cautiously to patients with a history of drug dependence or alcoholism. Chronic abusive use can lead to marked. Formulation Pearls (capsule). Duration of Effect 8–12 hours. Initial Dose 5 mg. Maximum daily dose 30 mg. Available unit dose forms 5, 10, 15, 20, 25, 30,

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If coadministration occurs, closely monitor patients for seizure activity.

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Patients receiving an H2-blocker should be monitored for adverse effects and reduced therapeutic efficacy of extended-release dexmethylphenidate. Moderate In theory, metoclopramide and dexmethylphenidate may interact pharmacodynamically to diminish the therapeutic effects of either agent through opposing effects on dopamine.

Major Concomitant use of cardiac glycosides with sympathomimetics can cause arrhythmias because sympathomimetics enhance ectopic pacemaker activity. Severe Safinamide is contraindicated for use with dexmethylphenidate due to the risk of serotonin syndrome. Monitor the patient for tremors, nervousness, increased heart rate, or other additive side effects.

Swallow whole or sprinkle contents onto applesauce swallow immediately ; do not crush, chew or divide beads. History of focallin dependence or alcoholism; monitor for abnormal behavior.

Moderate Because inserr the potential risk and severity of serotonin syndrome, caution should be observed when coadministering drugs that have serotonergic properties such as dexmethylphenidate xd St.

Serious side effects such as nervousness, irritability, arrhythmias, palpitations, seizures, or other stimulant-related adverse effects may occur or get worse during concurrent use. Pimozide and dexmethylphenidate may interact pharmacodynamically to diminish the therapeutic effects of either agent through opposing effects on dopamine. If swallowing is difficult, the capsule may be opened and the contents gently sprinkled on one tablespoon of cold applesauce not warm- warm applesauce could change the characteristics of the medication and swallowed.

If paradoxical aggravation of symptoms or other adverse effects occur, reduce dosage or discontinue the drug. The authors concluded that although the absolute magnitude of risk appears to be low, a modest increase packag risk could not be ruled out. Dexmethylphenidate is contraindicated in patients with known hypersensitivity to dexmethylphenidate, methylphenidate, or packahe components of these products. Patients should be monitored for heart rate, blood pressure, and for sedation during ADHD treatment.


Serotonin syndrome risk increases when 2 or more drugs with this effect are used packate. Drugs that reduce catecholamine uptake or deplete catecholamine stores, such as sympathomimetics, may interfere with iobenguane I uptake into cells and interfere with dosimetry calculations resulting in altered iobenguane I efficacy.

A MedGuide is available which informs patients about the cardiac and psychiatric risks associated with use, and should be provided by the authorized dispenser to each patient receiving a prescription.

Moderate Halogenated anesthetics e. Patients receiving a PPI should be monitored for adverse effects and reduced therapeutic efficacy of extended-release dexmethylphenidate. Peripheral vascular disease, Raynaud’s phenomenon.

Major Avoid use of sympathomimetic agents with iloprost. As with MAOIs, the use of a sympathomimetic drug with procarbazine may precipitate hypertensive crisis or other serious side effects. If use is necessary within 2 weeks of the MAOI drug, in general the initial dose of the sympathomimetic agent must be greatly reduced.

The use of dexmethylphenidate may cause dizziness, mask signs of fatigue or the need for rest, pzckage impair the ability of a patient to participate in activities that require mental alertness. There are no adequate studies in human pregnancy. Intravenous vasopressors may fodalin used in the emergency management of pulmonary hypertension patients when needed, but hemodynamic monitoring and careful monitoring of cardiac status are needed to avoid ischemia and other complications.

Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Moderate Dexmethylphenidate can reduce the hypotensive effect of antihypertensive agents, including indapamide. For pediatric patients, the AHA states that it is reasonable to obtain a baseline ECG as a part of the initial evaluation. Blue-Green Opaque Therapeutic Category: Sympathomimetics counteract the medications used to stabilize pulmonary hypertension, including iloprost.

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Debilitated or geriatric patients may be more susceptible to the CNS and sympathomimetic side effects of the amphetamines; use with caution in the older adult.

It should be noted packwge not all children with ADHD will require medication; non-drug measures are often instituted concurrently with drug therapy. In the presence of MAOIs, drugs that cause release of norepinephrine induce severe cardiovascular and cerebrovascular responses. Once this issue is excluded, use together may proceed with caution. Major Sympathomimetics, such as amphetamines, phentermine, and decongestants e.


Vasopressors include medications such as epinephrine, dopamine, midodrine, and non-prescription medications including pseudoephedrine and phenylephrine. The product catalog provides you with a full listing of Teva’s brand and generic product lines.

Aggression, hostility, and suicidal ideation or behaviors have been reported in both clinical trials and post-marketing experience with ADHD medications. Severe In general, all types of sympathomimetics and psychostimulants should be avoided in packxge receiving MAOIs due to an increased risk of hypertensive crisis. Children and Adolescents 6 years and older. Severe Pakage effects and increased toxicity may be observed when using cocaine in combination with other sympathomimetics. All patients being considered for treatment with stimulant medications should have a careful history taken, including assessment for a family history of sudden death or ventricular arrhythmias, and a physical exam to assess for the presence of cardiac disease.

Major The use of modafinil with other psychostimulants, including dexmethylphenidate, has not been adequately studied. There is little or no in vivo interconversion to the l-threo-enantiomer. Patients receiving calcium carbonate should be monitored for adverse effects and reduced therapeutic efficacy of extended-release dexmethylphenidate.

The drug exhibits activity similar to that of the amphetamines, although focallin underlying pharmacology for these two drug classes may differ. Learn how to get this Teva generic Teva’s generic xf are available in most pharmacies across the United States, though not all pharmacies carry the same Teva medications.

Patients receiving combination therapy of armodafinil with other psychostimulants should be closely observed for signs of nervousness, irritability, insomnia, arrhythmias, or other stimulant-related side effects. Further study is needed to fully assess the benefits and risks that may occur from concomitant administration of dexmethylphenidate and lithium.

Moderate Administer sympathomimetics with caution with beta-agonists such as indacaterol.

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