Erythema multiforme is divided into major and minor forms and is now regarded as distinct from Stevens–Johnson syndrome (SJS) and toxic epidermal. dermal necrolysis, where erythema multiforme minor is the mildest type .. Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y. Find out about erythema multiforme, a skin reaction that usually causes a rash for a few weeks.

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It presents with a skin eruption characterised by a typical target lesion. Diseases of the skin and appendages by morphology. Although access to this website is not restricted, the information found here is intended for use by medical providers.

Updated by Dr Delwyn Dyall-Smith, Epidermal nekrolyse, toksiskToksisk epidermal nekrolyseLyells syndrom. Views Read Edit View history. EM minor usually involves the skin and sometimes mouth sores.

Erythema Multiforme

It results primarily from a toxic reaction to various drugs, but occasionally eritrma as a result of infection, neoplastic conditions, or other exposure. Br J Oral Maxillofac Surg. It has been suggested that steroids used to treat EM major decrease the duration and severity of symptoms.

Complications of EM may include: There are usually no prodromal symptoms in erythema multiforme minor.

It is currently believed that EM is a result of an immune reaction to an inciting infectious or pharmacologic antigen. But bacteria, fungi, and other viruses also can cause someone to develop the condition. Start quickly Come back Spread Be raised or discolored Look like hives Have a central sore surrounded by pale red rings, also called a target, iris, or bulls-eye Have liquid-filled bumps or blisters of various sizes Be located minr the upper body, legs, arms, palms, hands, or feet Include the face or lips Appear evenly on both sides of the body symmetrical Multigorme symptoms may include: Answer Erythema multiforme is relatively common in children.


Mucosal changes, if present, consist initially of redness of the lips and inside cheek.

Erythema multiforme

Mild forms of EM usually get better in 2 to 6 weeks, but the problem may return. It is characterized by raised, edematous papules in the extremities; involvement of one or more mucous membranes; and epidermal detachment involving less than miinor percent of the total body surface area.

The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. It often takes on the classical “target lesion” appearance, [4] with a pink-red ring around a pale center.

There is a genetic tendency to erythema multiforme. Prevention Patient Education when prescribing drugs associated with Stevens-Johnson Immediately stop suspected drug see causes above if symptoms suggestive of Stevens-Johnson Skin pain, redness or Blister development with systemic symptoms e. Self-skin examination New smartphone apps to check your skin Learn more Sponsored content.

Erythema multiforme – NHS

Two types, one mild to moderate and one severe, are recognized erythema multiforme minor and erythema multiforme major. A few people may get the rash after taking certain medications, such as seizure medicines, anesthesia medicines, nonsteroidal anti-inflammatory medicines e.

Definition MSH An exfoliative disease of skin seen primarily in adults and characterized by flaccid bullae and spreading eritea so that the skin has the appearance of being scalded. In cases where the herpes simplex virus is thought to be causing the rash to return, doctors might prescribe a daily antiviral medicine.

The mild form usually presents with mildly itchy but itching can be very severepink-red blotches, symmetrically arranged and starting on the extremities. Retrieved 28 November Dark band of erythema Distribution: Back Links pages that link to this page.


In erythema multiforme major, one or more mucous membranes are typically affected, most often the oral mucosa:. This article has been cited by other articles in PMC. Erythema multiforme eriema frequently self-limiting and requires no treatment. Support Center Support Center. Disease or Syndrome T Erythema multiforme Stevens-Johnson syndrome —chart review of hospitalized patients.

Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis in children: Erythema multiforme EM Munor multiforme minor of the hands note the blanching centers of the lesion Specialty Dermatology Erythema multiforme EM is a skin condition of unknown cause; muktiforme is a type of erythema possibly mediated by deposition of immune complexes mostly IgM -bound complexes in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure.

Pathogenesis, clinical features, and diagnosis”.

However, erythema multiforme may eritma when the aciclovir is ceased. Erythema multiforme eventually goes away on its own. Towards evidence based emergency medicine: Most people who get erythema multiforme have no long-term problems.

Erythema multiforme in children

EM occurs mostly in adults 20 to 40 years old. The single most common trigger multiforms developing erythema multiforme is herpes simplex virus HSV infectionusually herpes labialis cold sore on the lip and less often genital herpes. Your health care provider will look at your skin to diagnose EM.

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