Available online at CURCUMA CAESIA ROXB. AND IT’S MEDICINAL. USES: A REVIEW. Sonjit Das, ProdyutMondal and Md. Kamaruz Zaman*. PDF | On Apr 19, , Sonjit Das and others published CURCUMA CAESIA ROXB. AND IT’S MEDICINAL USES: A REVIEW. Black turmeric is known to have certain medicinal values. The curcumin content when I read certain papers, It was very low ~ %. Now I am wondering.

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Bioactive curcumw in Curcuma caesia Roxb. The chemistry of free radicals and related reactive species; pp. The crude extracts of each solvent were dried in water bath and kept for further uses. The methanolic extract of Curcuma caesia Roxb. Aqueous extract of Iranian green tea prevents lipid peroxidation and chronic ethanol liver toxicity in rats.

Standard curve cwesia gallic acid to find out the total phenolic content. Antimutagenicity testing For the experiment with S9 mix, 0. Likewise the crude methanolic, ethyl acetate and aqueous extract showed scavenging activity with a percent decrease of When reactive oxygen species are present at a certain concentration the bond between O and H is broken. Many researchers have investigated that the increase levels of antioxidants present curckma plants are believed to decrease the oxidative damage and its harmful effects [9].

S9 is the mitochondrial enzyme mix required for metabolic activation of indirect acting mutagens like cyclophosphamide.

Reducing power methods indirectly evaluates the antioxidant activity Qureshi et al. Banerjee A, Nigam SS. Table 3 Superoxide anion scavenging ability of standard and methanolic extract of Curcuma caesia Roxb. The water is poured in the cauldron such that the rhizomes are completely covered.

March Learn how and when to remove this template message. The rhizomes of Curcuma caesia Roxb. SUMMARY Cancer is characterized by uncontrolled growth of cells and much research has been done for the past several years from various disciplines for the treatment of cancer but till now no therapy has been discovered.


Considerable attention has been focussed in recent years on the exploration of phytotherapeutic agents crucuma the treatment of oxidative stress and mutation related disorders. Metabolism of cyclophosphamide by rat hepatic microsomes. Literature reviews of Sarangthem and Haokip [41] also confirms that maximum curcuminoids, oil content, flavonoids, phenolics, different important amino acids, protein and high alkaloids are contained in the rhizome of this species.

Support Center Support Center. The mechanism that contributes to the antioxidant capacity of phenols and flavanoids include free radical scavenging ability, hydrogen or electron donation ability, chelation of redox active metals ions, modulation of gene expression and interaction with the cell signalling pathways [36].

Non enzymatic antioxidant defence systems. Cyclophosphamide CP is a nitrogen mustard alkylating agent[ 6 ] used in various types of cancer chemotherapy, but the International Agency for Research Centre has identified it as a carcinogen for both animals and humans. Comparison of the mutagenicity and teratogenicity of cyclophosphamide and its active metabolites, 4-hydroxycyclophosphamide, phosphoramide mustard, and acrolein.

The experimental animals were divided into eight groups each containing five mice designated as follows: The present results cufcuma the antimutagenic activity in Ames test that may be curcuna in part to powerful radical scavenger associated with the extract.

The reaction mixture was prepared by mixing 0. Determination of blood total, reduced, and oxidized glutathione in pediatric subjects. Recent advances in the chemoprevention of cancer.

Curcuma caesia – Wikipedia

New Central Book Agency; Stimulation of cyclophosphamide-induced pulmonary microsomal lipid peroxidation by oxygen. Peroxidation of lipids produces an end product, malondialdehyde MDA which disrupts the cell membrane, thereby increasing permeability to ions.

Prodrugs – from serendipity to rational design.


Superoxide dismutase assay It was performed following[ 27 ] with slight modifications. Traditional West African pharmacopeia, plants and derived compounds for cancer therapy. The chemistry behind antioxidant capacity assays. But their amount was found to be reduced with the administration of the extract at different concentrations.

xaesia In-vitro evaluation of antioxidant activity of Curcuma caesia Roxb. Preliminary phytochemical screening reveals the presence of alkaloids, carbohydrates, reducing sugars, flavonoids, terpenes, steroids, and tannins in the methanolic extract of C.

Antioxidant and Antimutagenic activity of Curcuma caesia Roxb. The importance of free radicals and catalytic metal ions in human diseases.

In fact, the tested extracts are the complex mixtures of several compounds, particularly phenolic compounds which have diverse chemical structures that determine various properties. Quantitative assay for lipid peroxidation The assay was performed following[ 31 ] with slight modifications.

In vivo assessment of DNA damage and protective effects of extracts from Miconia species using the comet assay and micronucleus test. This page was last edited on 6 Decemberat S9 preparation S9 is the mitochondrial enzyme mix required for metabolic activation of indirect acting mutagens like cyclophosphamide.

Curcuma caesia

The assay was performed following[ 31 ] with slight modifications. MECC has high phenol content,[ 22 ] it is also a good source of antioxidant and antimutagenic activity. Reducing power assay The ability to reduce ferric ions to ferrous ions by the vaesia present in rhizomes of C. Articles needing additional references from March All articles needing additional references Articles with ‘species’ microformats All articles with unsourced statements Articles with unsourced statements from February

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