Noma is an opportunistic infection promoted by extreme poverty. It evolves rapidly from a gingival inflammation to grotesque orofacial gangrene. Cancrum oris. Prevalence: Unknown; Inheritance: ; Age of onset: Childhood; ICD A; OMIM: ; UMLS: C; MeSH: D; GARD: Cancrum oris or noma (from the Greek nomein, “to devour”)1 is a “gangrenous affection of the mouth, especially attacking children in whom the constitution is.

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Ann Plast Surg ; When to Cabcrum a Medical Professional. From Wikipedia, the free encyclopedia. Disease definition Noma is a gangrenous disease that causes severe destruction of the soft and osseous tissues of the face. Leptospira Leptospira interrogans Leptospirosis. J Pak Assoc Dermatol ; Noma is a rapidly progressive, polymicrobial, often gangrenous infection of the mouth or genitals. Aesthetic restoration of facial defect caused by cancrum oris: The destruction of the bones around the mouth causes deformity of the face and loss of teeth.

They may also have a weakened immune system. Noma can also affect the genitals, spreading to the genital skin this is sometimes called noma pudendi.

Its exact prevalence is unknown. Post-operative photograph after reconstruction Click here to view.

Noma (disease) – Wikipedia

Cancrum oris in an adult Caucasian female. The aetiology remains unknown. In other projects Wikimedia Commons. Bednar’s aphthae Cleft palate High-arched palate Palatal cysts of the newborn Inflammatory papillary hyperplasia Stomatitis nicotina Torus palatinus.

A type of malnutrition called Kwashiorkorand other forms of severe protein malnutrition Poor sanitation and dirty living conditions Disorders such as measles or cancrim Living in a developing oria. However, it can cause severe scarring and deformity. Acute necrotizing gingivitis ANG and oral herpetic ulcers are considered the antecedent lesions, and ongoing studies suggest orie the rapid cancrkm of these precursor lesions to noma requires infection by a consortium of micro-organisms, with Fusobacterium necrophorum Fn and Prevotella intermedia Pi as the suspected key players.


Salivary glands Benign lymphoepithelial lesion Ectopic salivary gland tissue Frey’s syndrome HIV salivary gland disease Necrotizing sialometaplasia Mucocele Ranula Pneumoparotitis Salivary duct stricture Salivary gland aplasia Salivary gland atresia Salivary gland diverticulum Salivary gland fistula Salivary gland hyperplasia Salivary gland hypoplasia Salivary gland neoplasms Benign: A physical exam shows inflamed areas of the mucous membranes, mouth ulcers, and skin ulcers.

These complications can occur: Eagle syndrome Hemifacial hypertrophy Facial hemiatrophy Oral manifestations of systemic disease. The risk factors are poverty, malnutrition, poor oral hygiene, residential proximity to livestock in unsanitary environments, and infectious diseases, particularly measles and those due to the herpesviridae.

Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms.

A devastating orofacial gangrene. Often they have had an illness such as measles, scarlet fever, tuberculosis, or cancer. Sushil Subedi, Oral and Maxillofacial surgeon and the head of Department. Once the cicatrisation stage is complete, stepwise reconstructive surgery aimed at relieving the stricture of the mouth and then reconstruction of the mandible and maxilla, cheek, lips and nose can be considered.

Chlamydophila psittaci Psittacosis Chlamydophila pneumoniae. By using this site, you agree to the Terms of Use and Privacy Policy.

Related articles Cancrum oris gangrenous stomatitis noma. Archived from the original on The buccal opening in these children is limited to between 0 and 10 mm making intake of solid foods problematic or impossible.


Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms.

Views Read Edit View history. Gangrene Bacterial diseases Health in Africa. Health care resources for this disease Expert centres 22 Diagnostic tests 0 Patient organisations 0 Orphan drug s 0.

Periapical, mandibular and maxillary hard tissues — Bones of jaws Agnathia Alveolar osteitis Buccal exostosis Cherubism Idiopathic osteosclerosis Mandibular fracture Microgenia Micrognathia Intraosseous cysts Odontogenic: BV4 non- proteobacterial G- primarily A00—A79—, — The mucous membranes of the mouth develop ulcersand rapid, painless tissue degeneration ensues, which can degrade tissues of the bones in the face. How to cite this article: Cancrum oris or noma is a rapidly spreading gangrenous stomatitis which occurs chiefly in debilitated or malnourished children, destroying the soft and hard tissue structures.

This can eventually destroy the soft tissue and bone. Trop Med Int Health. Clinical description In addition to the severe facial destruction, cancurm with noma often present with rhinolalia aperta, uncontrollable drooling, and socially handicapping halitosis. Confounding interactions of malnutrition with infection. Only comments seeking to improve the kris and accuracy of information on the Orphanet website are accepted. Survivors of this disease suffer severe facial deformity due to loss of facial tissues and scarring.

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